Cosmetic Medicine · BYGOLDEN Melbourne
Two regenerative treatments, two different approaches, one shared goal. Here is how they compare, and how to find your starting point at BYGOLDEN in Parkdale.
How they compare
Rejuran and PRF are both regenerative injectables. Rather than adding volume or resurfacing the skin from the outside, both work beneath the surface to support your skin's own repair processes.
Where they differ is in what is introduced. Rejuran uses highly purified polynucleotides to support cellular repair and skin quality. PRF is prepared from a small sample of your own blood, releasing growth factors gradually over the days that follow.
Neither is universally better. The right choice depends on your skin, your concerns and your preferences, which is why a consultation comes first.
A clear look at what sets each treatment apart, so you can arrive at your consultation with the right questions.
Rejuran works with your skin's own biology, using highly purified polynucleotides to support cellular repair and collagen production from within.
Rather than treating the surface alone, it addresses the underlying factors behind rough texture, loss of firmness and tired-looking skin. Results are not designed to peak and fade. They tend to build with each session.
PRF, or Platelet Rich Fibrin, is prepared from a small sample of your own blood. It is processed to concentrate platelets and fibrin, then reintroduced to the areas being treated.
The fibrin scaffold releases growth factors gradually, supporting collagen and skin renewal over the days that follow. Because it is entirely autologous, it appeals to those who prefer to work only with their own biology.
These are general guides only. Your clinician will recommend the most appropriate approach for you at your consultation.
Both treatments begin the same way. A considered conversation, a thorough assessment and a recommendation built around your skin. If treatment is right for you, it can begin at the same appointment.
BYGOLDEN · 230 Como Parade West, Parkdale VIC 3195Individual results may vary. All treatments at BYGOLDEN are subject to a consultation to determine suitability. Regenerative injectable treatments require doctor assessment and prescription where applicable. The information on this page is general in nature and does not constitute medical advice. Last reviewed June 2026.