About this treatment

Skin renewal,
from the inside out.

Rejuran Tone Up is an advanced skin booster formulated with highly purified polynucleotides — a biocompatible compound derived from salmon DNA that has been used in medical and aesthetic settings for decades. Applied topically during microneedling, it is delivered directly into the skin where it supports natural cellular regeneration and repair.

Rather than adding volume or masking the skin's surface, Rejuran Tone Up works with your skin's own biology — strengthening the skin barrier, supporting collagen production and gradually improving tone, texture and clarity from within.

Results develop progressively over a series of treatments, producing healthier, more resilient skin that continues to improve over time.

What it may help with

Commonly used to address

Skin texture and tone

May assist in refining uneven skin texture and tone, producing a smoother, more polished complexion as the skin's renewal process is progressively activated.

Post-acne marks and pigmentation

May support improvement in post-acne marks and mild pigmentation over a course of treatments, as cellular repair and regeneration is encouraged from within.

Skin barrier strength

Polynucleotides actively support the skin's barrier function — helping to improve resilience, reduce sensitivity and strengthen the skin's ability to retain moisture over time.

Firmness and collagen support

May contribute to improved skin density and firmness as collagen production is supported — producing a more lifted, healthier appearance that develops gradually.

Dull or fatigued skin

May restore natural radiance and clarity to skin that appears dull or tired, as cellular regeneration and barrier repair take effect across a treatment course.

Neck and delicate areas

Suitable for use on the face, neck and other delicate areas — making it an effective option for addressing skin quality concerns beyond the face alone.

Rejuran Tone Up skin booster at BYGOLDEN

The BYGOLDEN approach

"Results that are built by your skin — not applied to it."

Rejuran Tone Up works with your skin's own regenerative capacity rather than simply coating the surface. By delivering polynucleotides directly into the skin during microneedling, the treatment activates repair at a cellular level — producing improvements in quality, resilience and tone that feel genuinely earned over time.

The process

How Rejuran Tone Up works

Phase one

Skin assessment

Your clinician assesses your skin concerns, sensitivities and goals before treatment begins. Rejuran Tone Up is tailored to your skin's specific condition — ensuring the right approach is taken for your individual needs and the areas being addressed.

Phase two

Microneedling delivery

The Rejuran Tone Up booster is applied topically and delivered into the skin via microneedling. This ensures the polynucleotides reach the deeper layers of the skin where they can most effectively support cellular repair and regeneration — with minimal downtime.

Phase three

Progressive skin renewal

In the weeks following each session, your skin's natural repair processes are activated — improving texture, tone and barrier strength over time. Results build progressively across a course of treatments, with ongoing improvement in overall skin quality.

Your questions

What to expect

Polynucleotides (PN) are highly purified, biocompatible compounds derived from salmon DNA. They have been used in medical and regenerative medicine for decades. In aesthetics, they are valued for their ability to support cellular repair, stimulate collagen production and strengthen the skin barrier — producing genuine improvements in skin quality over time.

Unlike hydrating skin boosters that primarily target moisture, Rejuran Tone Up works at a cellular level — supporting actual skin repair and regeneration rather than surface hydration alone. The results are more structural in nature, contributing to genuine improvements in skin density, barrier function and clarity over time.

Downtime is minimal. As the booster is delivered via microneedling, you may experience mild redness, warmth and slight swelling in the hours following treatment — similar in appearance to mild sun exposure. This typically resolves within 24 to 48 hours. You will receive detailed aftercare guidance from your clinician.

Some clients notice an initial improvement in skin clarity and radiance in the days following treatment. The most meaningful results — in texture, tone and skin quality — develop progressively over several weeks as your skin's renewal process takes effect. A course of treatments produces the most lasting improvement.

The number of sessions recommended will depend on your skin concerns and goals. Your clinician will discuss a treatment plan at your skin assessment. Most clients see the most significant improvement across a structured course of sessions spaced several weeks apart.

Rejuran Tone Up is suitable for the face, neck and other delicate areas. Your clinician will confirm the most appropriate treatment zones based on your individual concerns during your skin assessment.

Rejuran Tone Up is suitable for most skin tones and types. Your clinician will assess your skin at a consultation to confirm suitability, discuss any contraindications and tailor the treatment to your specific concerns.

Ready to begin

Book your Rejuran Tone Up appointment

Your clinician will assess your skin, discuss your concerns and design a treatment program around your goals — before any treatment is proceeded with.

Book appointment Call 03 7047 7704

Treatment summary

Delivery methodMicroneedling

DowntimeMinimal

Treatment areasFace, neck & more

Skin typesAll skin tones

CourseTailored to you

RejuranTone UpBooster

Skin renewal,from the inside out.

Commonly used to address

How Rejuran Tone Up works

What to expect

Book your Rejuran Tone Up appointment

Rejuran
Tone Up
Booster

Skin renewal,
from the inside out.